Friday, April 1, 2011

Anti depression medication discontinuation syndrome last between one to four weeks


ANTI DEPRESSION MEDICATIONS

Antidepressant psychotropic drugs used to relieve mood disorders like depression and dysthymia and anxiety disorders, such as social anxiety disorder. Drugs such as monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants (TCAs), tetracyclic antidepressants (TeCAs), the selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs) are more commonly associated at the end. These drugs are commonly prescribed by psychiatrists and other physicians, and their effectiveness and side effects have been many studies and competing demands. Many drugs produce an antidepressant effect, but the restrictions have caused controversy, and the risk of off-label prescriptions, though the strength of the arguments.

Thymoleptic effectiveness of modern antidepressants have never been conclusively shown to be more active than placebo according to two reviews of the Cochrane Collaboration. Review away, all studies of antidepressants has not been delivered to the FDA, published and unpublished, was excluded by the FDA in 2004. The literature on anti-depressants to 94% success in treating depression. Arrested in the literature, were less than 50% of success. Combined, all studies have shown that 51% of power - only two points better than a placebo. This increases the effectiveness of antidepressants other than the apparent 11% to 69% in the mirtazapine are exceptions placebo.Possible - norepinephrine and serotonin antagonist with effects opposite to that SSRIs and SNRIs - and venlafaxine, SNRI significant similarity between the chemical structure of the derivative of opioids tramadol.

Opioids have been used to treat major depression until the late 1950s. Amphetamines were used until mid 1960. Prescription opioids or amphetamines for depression fall into a legal gray area. Research has rarely been implemented in the therapeutic potential of opiates for depression over the past 60 years, while amphetamine has found a thriving market conditions, which largely dressed Attention Deficit Disorder, narcolepsy, and obesity, and continue to be studied for multiple applications. Both opiates and amphetamines cause a therapeutic response very quickly, results in 24-48 hours, the therapeutic ratio for opiates and amphetamines is greater than the tricyclic antidepressants.

Some of these small, very limited research, the opioid buprenorphine has demonstrated the greatest potential for the treatment of severe depression resistant to treatment with any drug known in a small study, it is generally recognized, and was released in 1995, but never pursued because of the stigma related to opioids, in addition, the Annex mental illness in America.

Most antidepressants have a  late-onset (2-6 weeks) and is usually given a few months to several years. Despite the name, antidepressants often controversial and with a lack of empirical evidence in support of their nomination, off-label to treat other conditions such as anxiety, obsessive-compulsive disorder, eating disorders, to chronic pain and certain hormone-induced disorders such as dysmenorrhea. Alone or in combination with anticonvulsants (eg, Tegretol or Depakote), these drugs used to treat Attention Deficit Hyperactivity Disorder (ADHD) and substance abuse by addressing the underlying depression. In addition, antidepressants have been used sometimes to treat snoring and headaches.

Other drugs that are not usually known as antidepressants,included low doses antipsychotics,   and benzodiazepines, can be used to control depression, although benzodiazepines - and all medications called antidepressants - physical dependence to form. Discontinuation of benzodiazepines (SSRI) treatment abruptly can cause unpleasant withdrawal symptoms. An extract of the herb plant is commonly used as an antidepressant, although labeled as a dietary supplement in some countries. antidepressants term is sometimes applied to any treatment (eg psychotherapy, electro-convulsive therapy, acupuncture) or process (eg, sleep disturbances, increased regular, gentle exercise) found to improve the mood clinical depression.

The number of antidepressants drugs prescribed by the NHS in the UK has almost doubled in a decade, authorities reported in 2010. In addition, the number increased sharply in 2009, when 39.1 million prescriptions were issued € 20,100,000 issued in 1999. In addition, doctors issued more than 3.18 million prescriptions in 2009 than in 2008. Health officials believe the increase is partly due to the recession. diagnosis, however, other reasons are improved, reducing the stigma of mental illness and distress caused by the economic crisis. Moreover, the concern of doctors is that some people with mild symptoms of depression medications are prescribed unnecessarily because of lack of other options, including talking therapies, counseling and cognitive-behavioral therapy.

Another factor that may increase the consumption of antidepressants is that these drugs are now used for other conditions, including social anxiety and PTSD.

If an  antidepressant drug such as SSRI medication is suddenly stopped, it can produce both psychological and physical symptoms, a phenomenon known as SSRI discontinuation syndrome . Once the decision was made to stop anti-depressants is a common practice to wean off slowly reducing the dose for several weeks. Most of the discontinuation syndrome last between one to four weeks. Selection of an antidepressant and dosage suitable for a certain thing and the person is a long and complex process that requires knowledge of a professional. Certain antidepressants can initially make depression worse, can cause anxiety, or it can make a patient aggressive, dysphoric or acutely suicidal. In rare cases, the antidepressant may cause transition from mania or hypomania, depression


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